PCA9543AD,112 Equivalent & Substitute Parts Reference

Part Overview

The PCA9543AD,112 is a 2-Channel I2C Multiplexer Interface manufactured by NXP USA Inc., designed for applications requiring I2C/SMBus signal routing and multiplexing. This component operates across a supply voltage range of 2.3V to 5.5V and is housed in a 14-SOIC package. The part is currently classified as Obsolete, which necessitates identification of functionally equivalent alternatives for ongoing design support and procurement continuity.

Substiute Parts

PCA9543AD,112

NXP USA Inc.In Stock: 997PCA9543AD,112 Datasheet

Current PartRFQ

PCA9543AD

Texas InstrumentsIn Stock: 3337PCA9543AD Datasheet

DirectRFQ

BU6521KV-E2

Rohm SemiconductorIn Stock: 2440BU6521KV-E2 Datasheet

MFR RecommendedRFQ

PCA9543ADR

Texas InstrumentsIn Stock: 5177PCA9543ADR Datasheet

MFR RecommendedRFQ

PI3HDX1204EZLEX

Diodes IncorporatedIn Stock: 2851PI3HDX1204EZLEX Datasheet

MFR RecommendedRFQ

PI4MSD5V9548AZDEX

Diodes IncorporatedIn Stock: 2222PI4MSD5V9548AZDEX Datasheet

MFR RecommendedRFQ

Z8523316ASG

ZilogIn Stock: 945Z8523316ASG Datasheet

MFR RecommendedRFQ

Key Parameters

Substitute Part Grouping Explanation

Substitution eligibility for the PCA9543AD,112 is determined by the following critical parameters:

• Functional Application: 2-Channel I2C Multiplexer capability
• Interface Protocol: I2C and SMBus compatibility
• Supply Voltage Range: 2.3V ~ 5.5V operational window
• Package Type: 14-SOIC form factor with 0.154" width (3.90mm)
• Mounting Technology: Surface Mount configuration
• Compliance Standards: ROHS3 compliance and REACH unaffected status

Substitute parts are grouped into two categories:

Category 1 - Direct Functional Equivalents (I2C Multiplexer, 14-SOIC Package)

• PCA9543AD (Texas Instruments)
• PCA9543ADR (Texas Instruments)

Category 2 - Functional Alternatives (Interface Specialization, Different Package)

• BU6521KV-E2 (Rohm Semiconductor) - Video Encoder, 48-VQFPC package
• PI3HDX1204EZLEX (Diodes Incorporated) - HDMI Redriver/Level Shifter, 32-TQFN package
• PI4MSD5V9548AZDEX (Diodes Incorporated) - Bus Switch 1x8:1, 24-TQFN package
• Z8523316ASG (Zilog) - Interface Specialized, 44-LQFP package

Parameter Comparison

Engineering Selection Recommendations

Primary Substitutes (Recommended for Direct Replacement)

PCA9543ADR (Texas Instruments) is the preferred substitute for the PCA9543AD,112. This part maintains identical electrical specifications (2.3V ~ 5.5V supply, I2C/SMBus interface) and package configuration (14-SOIC). The PCA9543ADR carries Active product status with 5,100 units in stock, ensuring long-term availability. Compliance certifications (ROHS3, REACH Unaffected, MSL 1) are equivalent to the original part.

PCA9543AD (Texas Instruments) provides an alternative direct equivalent with Last Time Buy status and higher inventory availability (3,290 units). This part is suitable for applications where extended procurement windows are acceptable.

Secondary Substitutes (Application-Dependent)

PI4MSD5V9548AZDEX (Diodes Incorporated) functions as a bus switch alternative with broader voltage support (1.65V ~ 5.5V) but requires circuit redesign due to different package (24-TQFN) and functional architecture (1x8:1 switching versus 2-channel multiplexing).

PI3HDX1204EZLEX (Diodes Incorporated) and Z8523316ASG (Zilog) are interface-category alternatives but operate at restricted voltage ranges (3.3V and 4.5V ~ 5.5V respectively) and require significant PCB layout modifications due to different package geometries.

BU6521KV-E2 (Rohm Semiconductor) is a video encoder IC with incompatible functional application and is not recommended as a substitute for I2C multiplexing applications.

Frequently Asked Questions (FAQ)

Q: Can PCA9543ADR directly replace PCA9543AD,112 without PCB modifications?

A: Yes. PCA9543ADR maintains identical package geometry (14-SOIC, 0.154" width), pin configuration, and electrical specifications (2.3V ~ 5.5V supply, I2C/SMBus interface). No PCB layout changes are required.

Q: What is the difference between PCA9543AD and PCA9543ADR?

A: Both parts are functionally identical 2-Channel I2C Multiplexers from Texas Instruments with matching electrical and package specifications. The primary difference is packaging format: PCA9543AD is supplied in Tube packaging, while PCA9543ADR is supplied in Cut Tape (CT) & Digi-Reel format. Product status differs (Last Time Buy versus Active), affecting long-term availability.

Q: Why are PI3HDX1204EZLEX and PI4MSD5V9548AZDEX listed as substitutes if they have different packages?

A: These parts are listed as functional alternatives based on the original part's substitute field data. However, they require circuit redesign and PCB layout modifications due to different package types (32-TQFN and 24-TQFN respectively) and functional architectures. They are not drop-in replacements.

Q: Is the PCA9543AD,112 still available for procurement?

A: The PCA9543AD,112 is classified as Obsolete. Direct procurement is limited. PCA9543ADR (Active status, 5,100 units in stock) or PCA9543AD (Last Time Buy status, 3,290 units in stock) are recommended alternatives.

Q: What compliance certifications should I verify for substitute parts?

A: All listed substitute parts maintain ROHS3 compliance and REACH Unaffected status, matching the original PCA9543AD,112. Moisture Sensitivity Level (MSL) ratings are equivalent (MSL 1) except for Z8523316ASG (MSL 3, 168 Hours), which requires controlled storage conditions.

Q: Can I use PI4MSD5V9548AZDEX as a 1:1 replacement?

A: No. PI4MSD5V9548AZDEX is a bus switch (1x8:1 circuit) with different functional architecture than the 2-channel I2C multiplexer. It requires complete circuit redesign and is not a drop-in substitute.

Q: What voltage range should I consider when selecting a substitute?

A: The original PCA9543AD,112 operates at 2.3V ~ 5.5V. PCA9543ADR maintains this range. If selecting alternative parts, verify that your system voltage falls within the substitute's specified range: PI3HDX1204EZLEX (3.3V only), PI4MSD5V9548AZDEX (1.65V ~ 5.5V), or Z8523316ASG (4.5V ~ 5.5V).