ISO7221MDRG4 Digital Isolator Equivalent & Substitute Parts

Part Overview

The ISO7221MDRG4 is a general purpose digital isolator manufactured by Texas Instruments, featuring 2500Vrms isolation voltage, 2 channels, and 150Mbps data rate in an 8-SOIC package. This part is discontinued at DiGi Electronics, necessitating identification of functionally equivalent alternatives for ongoing design support and procurement.

Key Parameters

Parameter	ISO7221MDRG4
Manufacturer	Texas Instruments
Technology	Capacitive Coupling
Number of Channels	2
Voltage - Isolation	2500Vrms
Data Rate	150Mbps
Common Mode Transient Immunity (Min)	25kV/µs
Propagation Delay tpLH / tpHL (Max)	16ns / 16ns
Voltage - Supply	3V ~ 5.5V
Operating Temperature	-40°C ~ 125°C
Package / Case	8-SOIC (0.154", 3.90mm Width)
Product Status	Discontinued at DiGi Electronics
RoHS Status	ROHS3 Compliant

Substitute Part Grouping Explanation

Substitution of the ISO7221MDRG4 is determined by the following critical parameters:

Primary Matching Criteria:

Isolation voltage: 2500Vrms (mandatory)
Number of channels: 2 (mandatory)
Package type: 8-SOIC (mandatory)
Channel configuration: Unidirectional, 1 input per side (mandatory)

Secondary Compatibility Factors:

Data rate capability (150Mbps or higher)
Common mode transient immunity (25kV/µs or higher)
Supply voltage range (must encompass 3V ~ 5.5V)
Operating temperature range
Coupling technology (capacitive, magnetic, or GMR acceptable)

Substitutes are grouped into two categories: direct manufacturer replacements from Texas Instruments and cross-manufacturer alternatives meeting all electrical and mechanical specifications.

Parameter Comparison

Part Number	Manufacturer	Technology	Channels	Data Rate	CMTI (Min)	tpLH/tpHL (Max)	Supply Voltage	Temp Range	Status
ISO7221MDRG4	Texas Instruments	Capacitive	2	150Mbps	25kV/µs	16ns / 16ns	3V ~ 5.5V	-40°C ~ 125°C	Discontinued
ISO7221MDR	Texas Instruments	Capacitive	2	150Mbps	25kV/µs	16ns / 16ns	3V ~ 5.5V	-40°C ~ 125°C	Active
ADUM1201ARZ	Analog Devices Inc.	Magnetic	2	1Mbps	25kV/µs	150ns / 150ns	2.7V ~ 5.5V	-40°C ~ 105°C	Active
ADUM1201ARZ-RL7	Analog Devices Inc.	Magnetic	2	1Mbps	25kV/µs	150ns / 150ns	2.7V ~ 5.5V	-40°C ~ 105°C	Active
ADUM1201BRZ	Analog Devices Inc.	Magnetic	2	10Mbps	25kV/µs	50ns / 50ns	2.7V ~ 5.5V	-40°C ~ 105°C	Active
ADUM1201BRZ-RL7	Analog Devices Inc.	Magnetic	2	10Mbps	25kV/µs	50ns / 50ns	2.7V ~ 5.5V	-40°C ~ 105°C	Active
ADUM1201CRZ	Analog Devices Inc.	Magnetic	2	25Mbps	25kV/µs	45ns / 45ns	2.7V ~ 5.5V	-40°C ~ 105°C	Active
ADUM1201CRZ-RL7	Analog Devices Inc.	Magnetic	2	25Mbps	25kV/µs	45ns / 45ns	2.7V ~ 5.5V	-40°C ~ 105°C	Active
IL 611-3E	NVE Corp/Isolation Products	GMR	2	100Mbps	15kV/µs	15ns / 15ns	3V ~ 5.5V	-40°C ~ 85°C	Active

Engineering Selection Recommendations

Tier 1 - Direct Replacement: ISO7221MDR is the primary substitute. Manufactured by Texas Instruments with identical electrical specifications and 8-SOIC packaging, this part maintains full compatibility with existing designs. Product status is Active with 5853 units in stock.

Tier 2 - Functional Equivalents (Magnetic Coupling Technology): The ADUM1201 series from Analog Devices Inc. provides 2500Vrms isolation in 2-channel, 8-SOIC configuration. Three speed grades are available:

ADUM1201ARZ / ADUM1201ARZ-RL7: 1Mbps (lowest speed grade)
ADUM1201BRZ / ADUM1201BRZ-RL7: 10Mbps (mid-range)
ADUM1201CRZ / ADUM1201CRZ-RL7: 25Mbps (highest speed grade)

All variants meet the 25kV/µs CMTI requirement and operate within the 3V ~ 5.5V supply range. Packaging variants (Tube vs. Cut Tape & Digi-Reel) accommodate different procurement workflows. These parts use magnetic coupling technology rather than capacitive coupling, with correspondingly higher propagation delays.

Tier 3 - Alternative Technology: IL 611-3E from NVE Corp employs GMR (Giant Magnetoresistive) technology with 2500Vrms isolation and 2 channels in 8-SOIC package. This part achieves 100Mbps data rate with 15ns propagation delay. Operating temperature range is -40°C ~ 85°C, which is narrower than the original part. CMTI is specified at 15kV/µs, below the 25kV/µs of the original specification.

Compliance Status: All recommended substitutes maintain ROHS3 compliance and REACH Unaffected status, consistent with the original part.

Frequently Asked Questions (FAQ)

Q: Can ISO7221MDR be used as a direct drop-in replacement for ISO7221MDRG4? A: Yes. ISO7221MDR is the active production equivalent with identical electrical specifications, channel count, isolation voltage, data rate, and 8-SOIC packaging. The only difference is product status (Active vs. Discontinued).

Q: What is the difference between ADUM1201ARZ, ADUM1201BRZ, and ADUM1201CRZ? A: These are speed-graded variants of the same base product. ARZ supports 1Mbps, BRZ supports 10Mbps, and CRZ supports 25Mbps. All three meet the 2500Vrms isolation and 25kV/µs CMTI requirements. Selection depends on the required data rate for your application.

Q: What does the "-RL7" suffix indicate on ADUM1201 parts? A: The "-RL7" suffix denotes Cut Tape & Digi-Reel packaging, as opposed to Tube packaging. Electrical specifications are identical; the suffix only indicates packaging format for procurement and handling.

Q: Why do ADUM1201 parts have higher propagation delays than ISO7221MDRG4? A: ADUM1201 uses magnetic coupling technology, while ISO7221MDRG4 uses capacitive coupling. Magnetic coupling inherently exhibits longer propagation delays (150ns for ADUM1201ARZ vs. 16ns for ISO7221MDRG4) but provides equivalent isolation performance and CMTI ratings.

Q: Is IL 611-3E a suitable substitute if my application requires 25kV/µs CMTI? A: IL 611-3E specifies 15kV/µs CMTI, which is below the 25kV/µs requirement of ISO7221MDRG4. This part is not recommended for applications requiring the full 25kV/µs specification.

Q: Are all substitute parts available in 8-SOIC packaging? A: Yes. All recommended substitutes are packaged in 8-SOIC (0.154", 3.90mm Width), maintaining mechanical compatibility with existing PCB layouts.

Q: What is the operating temperature difference between ISO7221MDRG4 and its substitutes? A: ISO7221MDRG4 operates -40°C ~ 125°C. ISO7221MDR matches this range. ADUM1201 series operates -40°C ~ 105°C (20°C narrower at the upper limit). IL 611-3E operates -40°C ~ 85°C (40°C narrower at the upper limit). Verify your application's temperature requirements before selection.

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