ISO7221MDG4 Digital Isolator Equivalent & Substitute Parts

Part Overview

The ISO7221MDG4 is a general purpose digital isolator manufactured by Texas Instruments, featuring 2500Vrms isolation voltage, 2 channels, and 150Mbps data rate with capacitive coupling technology. This part is discontinued at DiGi Electronics, necessitating identification of functionally equivalent alternatives for ongoing design support and procurement.

Key Parameters

Parameter	ISO7221MDG4
Manufacturer	Texas Instruments
Technology	Capacitive Coupling
Number of Channels	2
Voltage - Isolation	2500Vrms
Common Mode Transient Immunity (Min)	25kV/µs
Data Rate	150Mbps
Propagation Delay tpLH / tpHL (Max)	16ns / 16ns
Voltage - Supply	3V ~ 5.5V
Package / Case	8-SOIC (0.154", 3.90mm Width)
Operating Temperature	-40°C ~ 125°C
RoHS Status	ROHS3 Compliant

Substitute Part Grouping Explanation

Substitution for the ISO7221MDG4 is determined by the following critical parameters:

Primary Substitution Criteria:

Number of Channels: 2 (unidirectional)
Voltage - Isolation: 2500Vrms
Package / Case: 8-SOIC (0.154", 3.90mm Width)
Common Mode Transient Immunity: 25kV/µs minimum

Secondary Compatibility Factors:

Data Rate: 150Mbps or higher
Propagation Delay: 16ns or lower
Supply Voltage Range: Must encompass 3V ~ 5.5V
Operating Temperature: Must support -40°C ~ 125°C or equivalent range

Substitutes are grouped into two categories: direct manufacturer equivalents from Texas Instruments (ISO7221MD, ISO721MD, ISO722MD) and cross-manufacturer alternatives from Analog Devices (ADUM1201 series) and NVE Corp (IL 611-3E). Cross-manufacturer alternatives employ different isolation technologies (magnetic coupling, GMR) but maintain electrical and mechanical compatibility within the specified parameters.

Parameter Comparison

Part Number	Manufacturer	Technology	Channels	Isolation (Vrms)	CMTI (kV/µs)	Data Rate (Mbps)	tpLH/tpHL (ns)	Supply (V)	Temp Range (°C)	Status
ISO7221MDG4	Texas Instruments	Capacitive	2	2500	25	150	16/16	3.0-5.5	-40 to 125	Discontinued
ISO7221MD	Texas Instruments	Capacitive	2	2500	25	150	16/16	3.0-5.5	-40 to 125	Last Time Buy
ISO721MD	Texas Instruments	Capacitive	1	2500	25	150	16/16	3.0-5.5	-40 to 125	Last Time Buy
ISO722MD	Texas Instruments	Capacitive	1	2500	25	150	16/16	3.0-5.5	-40 to 125	Obsolete
ADUM1201ARZ	Analog Devices	Magnetic	2	2500	25	1	150/150	2.7-5.5	-40 to 105	Active
ADUM1201ARZ-RL7	Analog Devices	Magnetic	2	2500	25	1	150/150	2.7-5.5	-40 to 105	Active
ADUM1201BRZ	Analog Devices	Magnetic	2	2500	25	10	50/50	2.7-5.5	-40 to 105	Active
ADUM1201BRZ-RL7	Analog Devices	Magnetic	2	2500	25	10	50/50	2.7-5.5	-40 to 105	Active
ADUM1201CRZ	Analog Devices	Magnetic	2	2500	25	25	45/45	2.7-5.5	-40 to 105	Active
ADUM1201CRZ-RL7	Analog Devices	Magnetic	2	2500	25	25	45/45	2.7-5.5	-40 to 105	Active
IL 611-3E	NVE Corp	GMR	2	2500	15	100	15/15	3.0-5.5	-40 to 85	Active

Engineering Selection Recommendations

Direct Replacement (Recommended): ISO7221MD is the manufacturer-recommended substitute, offering identical electrical specifications and the same 8-SOIC package. This part maintains capacitive coupling technology and full parameter compatibility with the discontinued ISO7221MDG4. Packaging is available in Tube format with substantial inventory (860,200 pcs).

Texas Instruments Single-Channel Alternatives: ISO721MD and ISO722MD provide single-channel configurations with identical isolation voltage, CMTI, data rate, and propagation delay specifications. These parts are suitable only for applications requiring single-channel isolation. ISO722MD is obsolete and should be avoided for new designs.

Analog Devices iCoupler® Series (ADUM1201): The ADUM1201 family offers active product status with multiple data rate variants (1Mbps, 10Mbps, 25Mbps). All variants maintain 2500Vrms isolation, 25kV/µs CMTI, and 2-channel configuration. Key differences include magnetic coupling technology, lower maximum operating temperature (105°C vs. 125°C), and extended supply voltage range (2.7V minimum). ADUM1201CRZ and ADUM1201CRZ-RL7 provide the highest data rate (25Mbps) within this family. Packaging variants include Tube and Cut Tape (CT) & Digi-Reel® options.

NVE Corp IsoLoop® Series (IL 611-3E): The IL 611-3E employs GMR (Giant Magnetoresistive) technology with 2500Vrms isolation and 25kV/µs CMTI. This part offers 100Mbps data rate with superior propagation delay (15ns) but features reduced CMTI (15kV/µs) and lower maximum operating temperature (85°C). Channel configuration is 2 inputs on Side 1, 0 on Side 2 (unidirectional).

Product Status Considerations: ISO7221MD is designated Last Time Buy, indicating limited future availability. For long-term supply assurance, Analog Devices ADUM1201 variants (Active status) provide the most reliable procurement path. NVE Corp IL 611-3E maintains Active status with established inventory.

Compliance: All listed substitutes maintain ROHS3 compliance and REACH Unaffected status, consistent with the original part.

Frequently Asked Questions (FAQ)

Q: Can ISO7221MD directly replace ISO7221MDG4? A: Yes. ISO7221MD is the manufacturer-recommended substitute with identical electrical and mechanical specifications. Both parts feature 2500Vrms isolation, 2 channels, 150Mbps data rate, and 8-SOIC packaging. The primary difference is packaging format (Tube vs. original packaging).

Q: What is the key difference between ISO7221MD and ISO721MD? A: ISO721MD is a single-channel variant, while ISO7221MD provides 2 channels. All other electrical parameters remain identical. ISO721MD is suitable only for applications requiring single-channel isolation.

Q: Why do ADUM1201 parts have lower maximum operating temperature? A: ADUM1201 variants are specified to -40°C ~ 105°C, compared to ISO7221MDG4's -40°C ~ 125°C. Applications requiring operation above 105°C must use Texas Instruments or NVE Corp alternatives.

Q: What is the advantage of ADUM1201CRZ over ADUM1201ARZ? A: ADUM1201CRZ provides 25Mbps data rate with 45ns propagation delay, compared to ADUM1201ARZ's 1Mbps data rate and 150ns propagation delay. ADUM1201CRZ is suitable for higher-speed applications.

Q: Can IL 611-3E replace ISO7221MDG4 in all applications? A: IL 611-3E maintains 2500Vrms isolation and 25kV/µs CMTI but features reduced maximum operating temperature (85°C) and lower CMTI specification (15kV/µs vs. 25kV/µs). Applications operating above 85°C or requiring 25kV/µs CMTI must use alternative parts.

Q: What is the difference between ADUM1201CRZ and ADUM1201CRZ-RL7? A: Both parts are electrically identical. ADUM1201CRZ is packaged in Tube format, while ADUM1201CRZ-RL7 uses Cut Tape (CT) & Digi-Reel® packaging. Selection depends on procurement and assembly requirements.

Q: Are all substitutes pin-compatible with ISO7221MDG4? A: All listed substitutes use 8-SOIC (0.154", 3.90mm Width) packaging. Pin compatibility must be verified against specific application schematics, as channel configuration and pin assignment may differ between manufacturers.

Q: Which substitute offers the best long-term availability? A: Analog Devices ADUM1201 variants maintain Active product status with substantial inventory levels (4,817 to 52,300 pcs). These parts provide the most reliable long-term procurement path compared to Texas Instruments Last Time Buy or Obsolete designations.

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