LKX2W221MESA45 Equivalent & Substitute Parts

Part Overview

The Nichicon LKX2W221MESA45 is a 220 µF, 450 V aluminum electrolytic capacitor in radial, can snap-in package configuration. This component is designed for audio applications and operates across a temperature range of -25°C to 105°C with a rated lifetime of 2000 hours at 105°C. The part is currently active in production and ROHS3 compliant, making it suitable for modern electronic equipment requiring reliable energy storage and filtering in high-voltage circuits.

Equivalent and substitute parts are identified when design requirements change, original inventory becomes unavailable, or performance improvements are needed while maintaining functional compatibility within the same application category.

Key Parameters

Parameter	Value
Capacitance	220 µF
Voltage Rating	450 V
Tolerance	±20%
Package Type	Radial, Can - Snap-In
Lead Spacing	0.394" (10.00 mm)
Physical Diameter	0.984" (25.00 mm)
Height (Seated Max)	1.850" (47.00 mm)
Mounting Type	Through Hole
Operating Temperature Range	-25°C to 105°C
Polarization	Polar

Substitute Part Grouping Explanation

Substitution eligibility for the LKX2W221MESA45 is determined by strict adherence to the following parameters:

Critical Parameters (Must Match):

Capacitance: 220 µF
Voltage Rating: 450 V minimum
Tolerance: ±20%
Package Type: Radial, Can - Snap-In
Lead Spacing: 0.394" (10.00 mm)
Physical Diameter: 0.984" (25.00 mm)
Height (Seated Max): 1.850" (47.00 mm)
Mounting Type: Through Hole
Polarization: Polar

Allowable Variations:

Voltage Rating: May exceed 450 V (higher voltage rating provides backward compatibility)
Lifetime @ Temperature: May exceed 2000 Hrs @ 105°C
ESR (Equivalent Series Resistance): Variations permitted when not specified in original part
Ripple Current: May exceed original specification
Manufacturer: Different manufacturers acceptable if all critical parameters align

The identified substitute parts meet all critical parameters and maintain full mechanical and electrical compatibility with the original LKX2W221MESA45 in through-hole PCB applications.

Parameter Comparison

Parameter	LKX2W221MESA45 (Nichicon)	381LR221M450J452 (CDE)	475MXH220MEFCSN25X45 (Rubycon)
Capacitance	220 µF	220 µF	220 µF
Voltage Rating	450 V	450 V	475 V
Tolerance	±20%	±20%	±20%
Lead Spacing	0.394" (10.00 mm)	0.394" (10.00 mm)	0.394" (10.00 mm)
Physical Diameter	0.984" (25.00 mm)	0.984" (25.00 mm)	0.984" (25.00 mm)
Height (Seated Max)	1.850" (47.00 mm)	1.850" (47.00 mm)	1.850" (47.00 mm)
Mounting Type	Through Hole	Through Hole	Through Hole
Operating Temperature Range	-25°C to 105°C	-25°C to 105°C	-25°C to 105°C
Polarization	Polar	Polar	Polar
Lifetime @ 105°C	2000 Hrs	3000 Hrs	2000 Hrs
ESR @ 120 Hz	Not Specified	603 mOhm	Not Specified
Ripple Current @ 120 Hz	1.05 A	1.42 A	1.4 A
RoHS Status	ROHS3 Compliant	ROHS3 Compliant	ROHS3 Compliant
Product Status	Active	Active	Active

Engineering Selection Recommendations

All three parts—the original LKX2W221MESA45 and the two substitute options (381LR221M450J452 and 475MXH220MEFCSN25X45)—are active products with ROHS3 compliance and REACH unaffected status, confirming their suitability for current manufacturing and regulatory requirements.

The 381LR221M450J452 (Cornell Dubilier Electronics) provides extended lifetime performance at 3000 hours @ 105°C compared to the original 2000-hour specification, with measurable ESR data (603 mOhm @ 120 Hz) and increased ripple current capacity (1.42 A @ 120 Hz). This part maintains identical voltage and capacitance ratings.

The 475MXH220MEFCSN25X45 (Rubycon) offers a higher voltage rating of 475 V while maintaining all other critical parameters at the original specification level. This elevated voltage rating provides additional safety margin in high-voltage audio applications.

Selection between these parts depends on application-specific requirements: choose the CDE part for extended operational lifetime, or the Rubycon part for increased voltage headroom. All three parts are mechanically and electrically interchangeable within through-hole PCB designs.

Frequently Asked Questions (FAQ)

Q: Can the 475MXH220MEFCSN25X45 (475 V) replace the LKX2W221MESA45 (450 V)?

A: Yes. The higher voltage rating (475 V vs. 450 V) is a backward-compatible upgrade. The capacitor will function correctly in circuits designed for 450 V operation.

Q: Are all three parts physically identical?

A: Yes. All three parts share identical mechanical specifications: 0.984" diameter, 1.850" seated height, 0.394" lead spacing, and radial snap-in package configuration. They are direct drop-in replacements on through-hole PCBs.

Q: What is the difference between the CDE and Rubycon substitutes?

A: The CDE 381LR221M450J452 provides extended lifetime (3000 Hrs @ 105°C vs. 2000 Hrs) and higher ripple current capacity (1.42 A @ 120 Hz vs. 1.05 A). The Rubycon 475MXH220MEFCSN25X45 offers higher voltage rating (475 V vs. 450 V) while maintaining the original 2000-hour lifetime.

Q: Do all parts meet current compliance standards?

A: Yes. All three parts are ROHS3 compliant, REACH unaffected, and carry active product status from their respective manufacturers.

Q: Can these parts be used interchangeably in audio applications?

A: Yes. All three parts are rated for audio applications and maintain the same capacitance (220 µF), tolerance (±20%), and operating temperature range (-25°C to 105°C). They are fully interchangeable in audio circuit designs.

Q: What is the lead spacing significance?

A: Lead spacing of 0.394" (10.00 mm) is a critical mechanical parameter that determines PCB hole pattern compatibility. All three parts share this specification, ensuring they fit existing through-hole layouts without modification.

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